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547.857.1.03/.04.057+547.857.1.-026.8 , - - 8-18178554 ...

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- 8-18178554 -3--3,7--1--2,6-

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^ - 8 -( )-3- -3,7- -1 - -2,6 - .

^ - 8-( )-3- -3,7 -1 - -2,6 - - .

. 7- 8-( )-3- -3,7- -1 - -2,6 - .

- B ruker-A L PH A. - V arian ( 200 M H z, -6, - ).

- V arian . : - 3 , 1 , - 70 ,

   

(7- 2-()-) 5,95 .., 7,51-8,06 .. (N i-H ) 11,09 ..

   

1. - / .. , .. // . - 2002. - 4. - . 69-72.

2. 3--7-(--^)-8-- / .. , .. , .. . // . - 2003. - 6. - . 248-250.

3. [,4- / .. , .. , .. . // . - 2004. - 5.

- . 141-143.

4. Louis D.Q. Fundamentals of heterocyclic chemistry: importance in nature and in the synthesis of pharmaceuticals / D.Q. Louis. - Wiley 2010. - 327 p.

5. Pat. 2010/0279969 USA, 6 A61K 31/70. Azido purine nucleosides for treatment of viral infections / R.F. Schinazi, J.W. Mellors, N.P. Sluis-Cremer [et al.]. - 12/599951; . 14.05.2008 ; . 04.11.2010;

514/45.

. . 2013. 4 (147). 21 207

6. Phosphodiesterase inhibitor 3-isobutyl-methyl-xanthine affects rabbit ovaries and oviduct / A.V. Sirotkin, P. Chrenek, S. Chadio [et al.] // European Journal of Pharmacology. - 2010. - Vol. 643. - P. 145-151.

7. Pat. 7763625 USA, 6 A01N 43/90. Agents for treating migraine / M. Takeuchi, P. Jefferson, M. Takayama [et al.]. - 10/587264 ; . 28.01.2005 ; . 27.06.2010; 514/263.2.

8. - 7-- 7,8- 3- / .. , .. , .. . // .

. .- 2006.- .4, .1(13).- .70-79.

9. . . / . . // . . - 1960. - . 21, 3. - . 221-228.

10. . . / . . , . . , . . . - . : , 1991. - 208 .

SYNTHESIS, PHYSICOCHEMICAL AND BIOLOGYCAL PROPERTIES OF SOME

N7-SUBSTITUED 8-(HYDROXYMETHYL)-3-METHYL-3,7-DIHYDRO-1-PURINE-2,6-DIONE

   

e-mail: artem555_86@mail.ru



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